“Riveting…an electrifying true crime story of the Mafia-smitten eighties and nineties. Suspenseful and multifaceted, The Gotti Wars can’t be missed.� —Esquire, The Best Nonfiction Books of the Year A “meticulous chronicle of good triumphing over evil� (The Washington Post) from the determined young prosecutor who, in two of America’s most celebrated trials, managed to convict famed mob boss John Gotti—and ultimately took down the Mafia altogether. John Gotti was without a doubt the flashiest and most feared Mafioso in American history. He became the boss of the Gambino Crime Family in spectacular fashion—with the brazen and very public murder of Paul Castellano in front of Sparks Steakhouse in midtown Manhattan in 1985. Not one to stay below law enforcement’s radar, Gotti instead became the first celebrity crime boss. His penchant for eye-catching apparel earned him the nickname “The Dapper Don;� his ability to beat criminal charges led to another: “The Teflon Don.� This is the captivating story of Gotti’s meteoric rise to power and his equally dramatic downfall. Every step of the way, Gotti’s legal adversary—John Gleeson, an Assistant US Attorney in Brooklyn—was watching. When Gotti finally faced two federal racketeering prosecutions, Gleeson prosecuted both. As the junior lawyer in the first case—a bitter seven-month battle that ended in Gotti’s acquittal—Gleeson found himself in Gotti’s crosshairs, falsely accused of serious crimes by a defense witness Gotti intimidated into committing perjury. Five years later, Gleeson was in charge of the second racketeering investigation and trial. Armed with the FBI’s secret recordings of Gotti’s conversations with his underboss and consigliere in the apartment above Gotti’s Little Italy hangout, Gleeson indicted all three. He “flipped� underboss Sammy the Bull Gravano, killer of nineteen men, who became history’s highest-ranking mob turncoat—resulting in Gotti’s murder conviction. Gleeson ended not just Gotti’s reign, but eventually that of the entire mob. A spellbinding, page-turning courtroom drama, The Gotti Wars “tells us in electrifying detail how the good guys finally won, how justice triumphed over evil, and how Gleeson himself was transformed by his long war� (Nelson DeMille).

A riveting, decades-in-the-writing memoir from the determined young prosecutor who, in two of America's most celebrated trials, managed to convict famed mob boss John Gotti-and subsequently took down the Mafia altogether. John Gotti was without a doubt the flashiest and most feared Mafioso in American history. He became the boss of the Gambino Crime Family in spectacular fashion-with the brazen and very public murder of Paul Castellano in front of Sparks Steakhouse in midtown Manhattan in 1985. Not one to stay below law enforcement's radar, Gotti instead became the first celebrity crime boss. His penchant for eye-catching apparel earned him the nickname "The Dapper Don;" his ability to beat criminal charges led to another: "The Teflon Don." This is the captivating story of Gotti's meteoric rise to power and his equally dramatic downfall. Every step of the way, Gotti's legal adversary-John Gleeson, an Assistant US Attorney in Brooklyn-was watching. When Gotti finally faced two federal racketeering prosecutions, Gleeson prosecuted both. As the junior lawyer in the first case-a bitter seven-month battle that ended in Gotti's acquittal-Gleeson found himself in Gotti's crosshairs, falsely accused of serious crimes by a defense witness Gotti intimidated into committing perjury. Five years later, Gleeson was in charge of the second racketeering investigation and trial. Armed with the FBI's secret recordings of Gotti's conversations with his underboss and consigliere in the apartment above Gotti's Little Italy hangout, Gleeson indicted all three. He "flipped" underboss Sammy the Bull Gravano, killer of nineteen men, who became history's highest-ranking mob turncoat-resulting in Gotti's murder conviction. Gleeson ended not just Gotti's reign, but eventually that of the entire mob. An epic, page-turning courtroom drama, The Gotti Wars is a brilliantly told crime story that illuminates a time in our nation's history when lawyers and mobsters dominated the news, but it's also the story of a tenacious young man, in the glare of the media spotlight, who mastered the art of becoming a great attorney.

Osteoarthritis is a disease that has been characterised historically by the focal destruction of cartilaginous tissue and hence, is defined as such. However, recent investigations have brought this pathology into contention with significant evidence implicating subchondral bone in the disease's pathophysiology. Early-stage primary osteoarthritic bone samples were harvested from both presenting medial and and non-presenting lateral compartments of diseased human tibia and were used to investigate the role of subchondral bone in the pathogenesis of primary human osteoarthritis. Significant differences in intrinsic tissue stiffness and mineralisation were observed in all samples presenting with clinically-defined, early-stage OA. Interstingly, non-presenting lateral samples also exhibited significant differences in stiffness and mineralisation. Hence, the presence of an early, non-presenting stage of OA initiation was observed in the bone tissue of these samples prior to overlying cartilaginous tissue damage. In conclusion, the classic 'wear' and 'tear' definition of this disease is no longer applicable to human knee OA.